Platelet-Rich Plasma Versus Hyaluronic Acid for Knee Osteoarthritis: A Systematic Review and Meta-analysis of Randomized Controlled Trials

John W. Belk, BA,Matthew J. Kraeutler, MD,Darby A. Houck, BA, Jesse A. Goodrich, BA,Jason L. Dragoo, MD, and Eric C. McCarty, MD

Platelet-rich plasma (PRP) and hyaluronic acid (HA) are 2 nonoperative treatment options for knee osteoarthritis (OA) that are supposed to provide symptomatic relief and help delay surgical intervention.
A systematic review of the literature to compare the efficacy and safety of PRP and HA injections for the treatment of knee OA. 

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